Why test IgG for food sensitivity?
There is a growing body of evidence to support the clinical benefits of eliminating IgG-reactive foods from the diet. IgG food sensitivities have been implicated in migraine headaches. Bloating and indigestion are also common food sensitivity reactions, as is fatigue. Because IgG food reactions take hours or days to develop, this makes it difficult to determine which food is responsible for the reaction without doing testing. Several research studies suggest there are benefits to performing food elimination diets based on what foods cause an IgG food reaction. We've included the studies below.
1. Alpay, K, et al. Diet restriction in migraine, based on IgG against foods: A clinical double-blind, randomised, cross-over trial. Sage Journals. Volume: 30 issue: 7, page(s): 829-837. Retrieved from: http://journals.sagepub.com/doi/abs/10.1177/0333102410361404
2. Arroyave Hernandez CM, et al. Food allergy mediated by IgG antibodies associated with migraine in adults. Rev Alerg Mex.2007 Sep-Oct;54(5):162-8. Retrieved from: https://www.ncbi.nlm.nih.gov/pubmed/18693538
3. Avdiniar, E, et al. IgG-based elimination diet in migraine plus irritable bowel syndrome. Headache. 2013 Mar;53(3):514-25. Retrieved from: https://www.ncbi.nlm.nih.gov/p
4. Carini, C., et al. Immune complexes in food-induced arthralgia. Ann Allergy.1987 Dec;59(6):422-8. Retrieved from:https://www.ncbi.nlm.nih.gov/pubmed/3425981
5. Dixon, HS. Treatment of delayed food allergy based on specific immunoglobulin G RAST testing. Otolaryngol Head Neck Surg.2000;123:48-54. https://www.ncbi.nlm.nih.gov/m/pubmed/10889481/
6. Wendy Hodsdon, ND and Heather Zwickey, PhD, (2010). Reproducibility and Reliability of Two Food Allergy Testing Methods. Natural Medicine Journal 2(3), March, 2010. Retrieved from: https://www.researchgate.net/publication/242659400_NMJ_Original_Research_Reproducibility_and_Reliability_of_Two_Food_Allergy_Testing_Methods
7. Yang, C. M. and Y. Q. Li (2007). “[The therapeutic effects of eliminating allergic foods according to food-specific IgG antibodies in irritable bowel syndrome].” Zhonghua nei ke za zhi [Chinese journal of internal medicine] 46(8): 641-643. Retrieved from: https://www.ncbi.nlm.nih.gov/pubmed/17967233
8. Drisko, J., B. Bischoff, et al. (2006). “Treating irritable bowel syndrome with a food elimination diet followed by food challenge and probiotics.” Journal of the American College of Nutrition 25(6): 514-522. Retrieved from: https://www.ncbi.nlm.nih.gov/p
9. Atkinson, W., T. A. Sheldon, et al. (2004). “Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial.” Gut 53(10): 1459-1464. Retrieved from: https://www.ncbi.nlm.nih.gov/p
10. Leszek Rudzki, Dariusz Pawlak, Krystyna Pawlak, Napoleon Waszkiewicz, Aleksandra Małus, Beata Konarzewska, Mirosława Gałęcka, Anna Bartnicka, Lucyna Ostrowska and Agata Szulc, The Author(s). 2017. "Immune suppression of IgG response against dairy proteins in major depression." Retrieved from: https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-017-1431-y
11. Hanna Karakula-Juchnowicz, Mirosława Gałęcka, Joanna Rog, Anna Bartnicka, Zuzanna Łukaszewicz, Pawel Krukow, Justyna Morylowska-Topolska, Karolina Skonieczna-Zydecka, Tomasz Krajka, Kamil Jonak, and Dariusz Juchnowicz. Nutrients 2018, 10(5), 548. "The Food-Specific Serum IgG Reactivity in Major Depressive Disorder Patients, Irritable Bowel Syndrome Patients and Healthy Controls." Retrieved from: https://www.mdpi.com/2072-6643/10/5/548/htm?fbclid=IwAR1QVuFpE6P1_eh2hu9zHw_DCe5s_AgfG_GCtVZOCuYulhsHKE-VEQBEDYg